Post-irradiation nasal nitric oxide in patients with nasopharyngeal carcinoma

Yan-Ting Ho; Ta-Jen Lee; Po-Hung Chang; Chia-Hsiang Fu

doi:10.1002/alr.23161

Post-irradiation nasal nitric oxide in patients with nasopharyngeal carcinoma

Int Forum Allergy Rhinol. 2023 Oct;13(10):1982-1986. doi: 10.1002/alr.23161. Epub 2023 Jun 28.

Authors

Yan-Ting Ho¹, Ta-Jen Lee¹, Po-Hung Chang^{1

2}, Chia-Hsiang Fu^{1

2}

Affiliations

¹ Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
² Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

PMID: 36965128
DOI: 10.1002/alr.23161

Abstract

nNO levels decreased at 3 and 6 months and recovered at 12 months after radiotherapy in NPC. nNO may be a feasible biomarker for mucociliary function in post-irradiated NPC patients. Lower nNO levels were associated with more sinonasal burdens in post-irradiated NPC patients.

Keywords: SNOT-22; chronic rhinosinusitis; clearance; mucociliary; nasopharyngeal carcinoma; quality of life.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chronic Disease
Humans
Nasopharyngeal Carcinoma / complications
Nasopharyngeal Carcinoma / radiotherapy
Nasopharyngeal Neoplasms* / radiotherapy
Nitric Oxide
Rhinitis*
Sinusitis*

Substances

Nitric Oxide