EMSY stabilization in KEAP1-mutant lung cancer disrupts genome stability and type I interferon signaling

Cell Death Differ. 2023 May;30(5):1397-1399. doi: 10.1038/s41418-023-01150-z. Epub 2023 Mar 23.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genomic Instability
  • Humans
  • Interferon Type I* / genetics
  • Kelch-Like ECH-Associated Protein 1 / genetics
  • Kelch-Like ECH-Associated Protein 1 / metabolism
  • Lung Neoplasms* / genetics
  • NF-E2-Related Factor 2 / genetics
  • NF-E2-Related Factor 2 / metabolism

Substances

  • Kelch-Like ECH-Associated Protein 1
  • NF-E2-Related Factor 2
  • Interferon Type I
  • KEAP1 protein, human