A survival analysis of socio-demographic and clinical predictors among hospitalized COVID-19 patients in Southern Iran

BMC Infect Dis. 2023 Mar 22;23(1):175. doi: 10.1186/s12879-023-08129-8.

Abstract

Background: This study aimed to evaluate the socio-demographic, clinical, and laboratory risk factors in hospitalized COVID-19 patients during the first 6 months of the SARS-CoV-2 epidemic.

Method: This retrospective hospital-based cross-sectional study included all laboratory-confirmed cases of the COVID-19 virus that were admitted to the Shohadaye-Khalije-Fars Hospital in Bushehr, Iran, from February 22, 2020 to September 21, 2020. The patients' records were reviewed during the hospitalization period. The global COVID-19 clinical platform, i.e., the World Health Organization Rapid Case Report Form was used as the data collection tool. We conducted the survival analysis using the Kaplan-Meier and the Stepwise Cox regression analyses.

Results: The analysis included 2108 confirmed cases of COVID-19 with a mean age of 47.81 years (SD 17.78); 56.8% men, 43.2% women and 6.3% (n = 133) deaths. After adjustment, it was found that factors associated with an increased risk of death consisted of chronic kidney disease, intensive care unit admission, cancer, and hemoptysis. The 7-day survival rate was 95.8%, which decreased to 95.1%, 94.0%, and 93.8% on days 14, 21, and 28 of hospitalization, respectively.

Discussion and conclusion: Older COVID-19 patients with manifestation of hemoptysis and a past medical history of chronic kidney disease and cancer, should be closely monitored to prevent disease deterioration and death, and also should be admitted to the intensive care unit.

Keywords: Bushehr; COVID-19; Iran; Mortality; Registry; Risk factors; Survival.

MeSH terms

  • COVID-19* / epidemiology
  • Cross-Sectional Studies
  • Demography
  • Female
  • Hemoptysis
  • Hospitalization
  • Humans
  • Iran / epidemiology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • SARS-CoV-2
  • Survival Analysis