Trends in the Synthesis of Polymer Nano- and Microscale Materials for Bio-Related Applications

Macromol Biosci. 2023 Aug;23(8):e2200474. doi: 10.1002/mabi.202200474. Epub 2023 Mar 22.

Abstract

Polymeric nano- and microscale materials bear significant potential in manifold applications related to biomedicine. This is owed not only to the large chemical diversity of the constituent polymers, but also to the various morphologies these materials can achieve, ranging from simple particles to intricate self-assembled structures. Modern synthetic polymer chemistry permits the tuning of many physicochemical parameters affecting the behavior of polymeric nano- and microscale materials in the biological context. In this Perspective, an overview of the synthetic principles underlying the modern preparation of these materials is provided, aiming to demonstrate how advances in and ingenious implementations of polymer chemistry fuel a range of applications, both present and prospective.

Keywords: bioapplications; biocompatibility; biomaterials; block copolymers; nano- and micromaterials; polymer synthesis; self-assembly.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Polymers* / chemistry
  • Prospective Studies

Substances

  • Polymers