Repair what is lost: Neuroprotection through neural stem cells in progressive MS

Menno M Schoonheim; Eva M M Strijbis

doi:10.1016/j.xcrm.2023.100985

Repair what is lost: Neuroprotection through neural stem cells in progressive MS

Cell Rep Med. 2023 Mar 21;4(3):100985. doi: 10.1016/j.xcrm.2023.100985.

Authors

Menno M Schoonheim¹, Eva M M Strijbis²

Affiliations

¹ MS Center Amsterdam, Anatomy and Neurosciences, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Amsterdam, the Netherlands. Electronic address: m.schoonheim@amsterdamumc.nl.
² MS Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam Neuroscience, Amsterdam UMC location VUmc, Amsterdam, the Netherlands.

Abstract

Genchi et al.¹ report the first phase 1 trial of neural stem cell transplantation in multiple sclerosis showing a reduction in gray matter atrophy. Results give hope for a new era of induced neuroprotection, especially in progressive multiple sclerosis.

MeSH terms

Gray Matter
Humans
Multiple Sclerosis* / therapy
Multiple Sclerosis, Chronic Progressive* / therapy
Neural Stem Cells*
Neuroprotection