Stellettin B renders glioblastoma vulnerable to poly (ADP-ribose) polymerase inhibitors via suppressing homology-directed repair

Signal Transduct Target Ther. 2023 Mar 22;8(1):119. doi: 10.1038/s41392-023-01324-8.

Xin Peng^#^{1

2

3}, Yingying Wang^#^{1

2}, Shaolu Zhang^#^{1

2}, Zhennan Tao⁴, Yuxiang Dai⁴, Francois X Claret³, Moshe Elkabets⁵, Hou-Wen Lin⁶, Zhe-Sheng Chen⁷, Dexin Kong^{8

9}

¹ Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
² Key Laboratory of Immune Microenvironment and Diseases (Ministry of Education), Tianjin Medical University, Tianjin, 300070, China.
³ Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
⁴ Department of Neurosurgery, the Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, 210008, China.
⁵ The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
⁶ Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, China. franklin67@126.com.
⁷ Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY, 11439, USA. chenz@stjohns.edu.
⁸ Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China. kongdexin@tmu.edu.cn.
⁹ Key Laboratory of Immune Microenvironment and Diseases (Ministry of Education), Tianjin Medical University, Tianjin, 300070, China. kongdexin@tmu.edu.cn.

^# Contributed equally.

No abstract available

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