Cationic Oligopeptides with Amino Groups as Synthetic Nucleolar Localization Signals for the Rational Design of Nucleolus-Staining Probes

Michiyuki Suzuki; Yusuke Sato; Nao Togashi; Seiichi Nishizawa

doi:10.1021/acsomega.3c00116

Cationic Oligopeptides with Amino Groups as Synthetic Nucleolar Localization Signals for the Rational Design of Nucleolus-Staining Probes

ACS Omega. 2023 Feb 28;8(10):9592-9596. doi: 10.1021/acsomega.3c00116. eCollection 2023 Mar 14.

Authors

Michiyuki Suzuki¹, Yusuke Sato¹, Nao Togashi¹, Seiichi Nishizawa¹

Affiliation

¹ Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.

Abstract

Cationic oligopeptides with amino groups were found to function as synthetic nucleolar localization signals for directing various fluorophores to the nucleolus with high selectivity in the cells with a view toward the development of nucleolus-staining probes.