Colorectal cancer with testicular metastasis: A case report and literature review

Medicine (Baltimore). 2023 Mar 17;102(11):e33214. doi: 10.1097/MD.0000000000033214.

Abstract

Rationale: Colorectal cancer is the second leading cause of cancer-related deaths in the world. About 50% of patients will have metastases during the course of the disease. The common sites of metastasis are the liver, lung, peritoneum, lymph, etc. Metastatic carcinoma to the testes is uncommon. We found a case of ascending colon cancer metastasized to the testis in the clinic.

Patient concerns: We reported a 50-year-old male patient who was found to have testicular metastases >4 years after intestinal cancer surgery, and multiple metastases in the peritoneum and pelvis were found 1 week later.

Diagnoses: After enhanced computed tomography and pathological biopsy, the patient was diagnosed with testicular metastasis of colon cancer.

Interventions: Capecitabine combined with bevacizumab is currently undergoing palliative treatment.

Outcomes: The patients died of tumor progression on June 28, 2021.

Lessons: The testicular metastasis of colorectal cancer is a sign of peritoneum and multiple metastases. When the testicular metastasis occurs in colorectal cancer patients, it usually indicates that the patient has a poor prognosis.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Adenocarcinoma* / pathology
  • Bevacizumab
  • Capecitabine / therapeutic use
  • Colonic Neoplasms*
  • Humans
  • Male
  • Middle Aged
  • Testicular Neoplasms* / pathology

Substances

  • Bevacizumab
  • Capecitabine