Relevance of body composition in phenotyping the obesities

Rev Endocr Metab Disord. 2023 Oct;24(5):809-823. doi: 10.1007/s11154-023-09796-3. Epub 2023 Mar 17.

Abstract

Obesity is the most extended metabolic alteration worldwide increasing the risk for the development of cardiometabolic alterations such as type 2 diabetes, hypertension, and dyslipidemia. Body mass index (BMI) remains the most frequently used tool for classifying patients with obesity, but it does not accurately reflect body adiposity. In this document we review classical and new classification systems for phenotyping the obesities. Greater accuracy of and accessibility to body composition techniques at the same time as increased knowledge and use of cardiometabolic risk factors is leading to a more refined phenotyping of patients with obesity. It is time to incorporate these advances into routine clinical practice to better diagnose overweight and obesity, and to optimize the treatment of patients living with obesity.

Keywords: BMI; Body composition; Body fat percentage; Cardiometabolic risk; Metabolic health; Obesity; Phenotyping; Visceral adipose tissue; Waist circumference.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adiposity
  • Body Composition
  • Body Mass Index
  • Diabetes Mellitus, Type 2* / diagnosis
  • Humans
  • Obesity
  • Risk Factors
  • Waist Circumference