Rhino sinusitis caused by Lasiodiplodia theobromae in a diabetic patient

Anand Kumar Maurya; Sweta Kumari; Ganakalyan Behera; Arati Bhadade; Karuna Tadepalli

doi:10.1016/j.mmcr.2023.02.002

Rhino sinusitis caused by Lasiodiplodia theobromae in a diabetic patient

Med Mycol Case Rep. 2023 Feb 18:40:22-24. doi: 10.1016/j.mmcr.2023.02.002. eCollection 2023 Jun.

Authors

Anand Kumar Maurya¹, Sweta Kumari¹, Ganakalyan Behera², Arati Bhadade¹, Karuna Tadepalli¹

Affiliations

¹ ICMR Mycology Advanced Resource Centre (iMARC), Department of Microbiology, All India Institute of Medical Sciences, Bhopal, 462020, India.
² Department of Otolaryngology (ENT) - Head and Neck Surgery, All India Institute of Medical Sciences, Bhopal, 462020, India.

Abstract

We report an uncommon instance of rhinosinusitis by Lasiodiplodia theobromae in a known diabetic patient. A melanized fungus called Lasiodiplodia theobromae causes a typical plant disease that rots fruits and plants. Infections in humans are currently limited. Mostly from tropical and subtropical regions, there have been few reported occurrences. The fungus has been associated with clinical manifestations such as onychomycosis, corneal ulcers, and phaeohyphomycosis. Identification by phenotype was inconclusive. DNA sequencing was used for final identification. Amphotericin B and surgical debridement were effective treatments for the patient.

Keywords: Antifungals; Debridement surgery; L. theobromae, Lasiodiplodia theobromae; L.parva, Lasiodiplodia parva; L.pseudotheobromae, Lasiodiplodia pseudotheobromae; Lasiodiplodia theobromae; Melanized; Rhinosinusitis.

Publication types

Case Reports