Nickel substituted polyoxometalates in layered double hydroxides as metal-based nanomaterial of POM-LDH for green catalysis effects

Azra Ghiasi Moaser; Ahmad Gholami Afkham; Roushan Khoshnavazi; Sadegh Rostamnia

doi:10.1038/s41598-023-31356-7

Nickel substituted polyoxometalates in layered double hydroxides as metal-based nanomaterial of POM-LDH for green catalysis effects

Sci Rep. 2023 Mar 13;13(1):4114. doi: 10.1038/s41598-023-31356-7.

Authors

Azra Ghiasi Moaser¹, Ahmad Gholami Afkham², Roushan Khoshnavazi³, Sadegh Rostamnia⁴

Affiliations

¹ Organic and Nano Group (ONG), Department of Chemistry, Iran University of Science and Technology (IUST), P.O. Box 16846-13114, Tehran, Iran.
² Department of Chemistry, University of Kurdistan, P.O. Box 66135-416, Sanandaj, Iran.
³ Department of Chemistry, University of Kurdistan, P.O. Box 66135-416, Sanandaj, Iran. r.khoshnavazi@uok.ac.ir.
⁴ Organic and Nano Group (ONG), Department of Chemistry, Iran University of Science and Technology (IUST), P.O. Box 16846-13114, Tehran, Iran. rostamnia@iust.ac.ir.

Abstract

Three nickel substituted Keggin-type polyoxometalates, α-[SiW₉O₃₇{Ni(H₂O)}₃]^-10 (denoted as SiW₉Ni₃), was intercalated into Zn₃Al based Layered Double Hydroxide (Zn₃Al-LDH) by the selective ion-exchange technique. The as-synthesized nanocomposite, SiW₉Ni₃@Zn₃Al, was used as heterogeneous nanoreactor to promote the synthesis of drug-like aminoimidazopyridine small molecule skeletons via the well-known Ugi-type Groebke-Blackburn-Bienaymé reaction (GBB 3-CRs) in the absence of any acid/additive and under mild and solvent-free conditions. A synergistic catalytic effect between SiW₉Ni₃ polyoxometalate and Zn₃Al-LDH precursors is evidenced by a higher catalytic property of the SiW₉Ni₃@Zn₃Al composite compared to the individual constituents separately. Lewis/Bronsted acidity of the SiW₉Ni₃ polyoxometalate and Zn₃Al-LDH precursors appear to be essential for the catalytic performance of the composite. Furthermore, the catalytic performance of SiW₉Ni₃@Zn₃Al was also tested in GBB 3-CRs synthesis of amino imidazothiazole under mild and solvent-free conditions.