Full-Thickness Macular Hole After Intravitreal Conbercept Injection in Branch Retinal Vein Occlusion

Pinxue Xie; Siquan Zhu; Ran Yan; Ping Wei; Xinxiao Gao

doi:10.7759/cureus.34660

Full-Thickness Macular Hole After Intravitreal Conbercept Injection in Branch Retinal Vein Occlusion

Cureus. 2023 Feb 5;15(2):e34660. doi: 10.7759/cureus.34660. eCollection 2023 Feb.

Authors

Pinxue Xie^{1

2}, Siquan Zhu¹, Ran Yan¹, Ping Wei³, Xinxiao Gao¹

Affiliations

¹ Ophthalmology, Beijing Anzhen Hospital, Capital Medical University, Beijing, CHN.
² Ophthalmology, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, CHN.
³ Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, USA.

Abstract

This article reports a case of macular hole (MH) formation following intravitreal conbercept injection for branch retinal vein occlusion (BRVO). A 70-year-old male received three consecutive intravitreal injections of conbercept for the treatment of macular edema secondary to BRVO in his left eye. Due to the outbreak of the COVID-19 epidemic, the patient was lost to follow-up. At two months follow-up, a full-thickness MH was detected by fundoscopic and optical coherence tomography examination. Fortunately, the MH was successfully closed after pars plana vitrectomy. MH is a rare complication following intravitreal injections for RVO, which should be considered by clinicians.

Keywords: anti-vegf; branch retinal vein occlusion; conbercept; intravitreal injections; macular hole.

Publication types

Case Reports