Chromogranin A: An Endocrine Factor of Pregnancy

Int J Mol Sci. 2023 Mar 5;24(5):4986. doi: 10.3390/ijms24054986.

Abstract

Pregnancy is a state of physiological and hormonal changes. One of the endocrine factors involved in these processes is chromogranin A, an acidic protein produced, among others, by the placenta. Although it has been previously linked to pregnancy, no existing articles have ever managed to clarify the role of this protein regarding this subject. Therefore, the aim of the present study is to gather knowledge of chromogranin A's function with reference to gestation and parturition, clarify elusive information, and, most importantly, to formulate hypotheses for the future studies to verify.

Keywords: catestatin; chromogranin A; pregnancy.

Publication types

  • Review

MeSH terms

  • Chromogranin A / metabolism
  • Chromogranins* / metabolism
  • Endocrine System* / metabolism
  • Female
  • Humans
  • Parturition
  • Peptide Fragments / metabolism
  • Placenta / metabolism
  • Pregnancy

Substances

  • Chromogranin A
  • Chromogranins
  • Peptide Fragments

Grants and funding

This research received no external funding.