Association between triglyceride glucose index and sleep disorders: results from the NHANES 2005-2008

BMC Psychiatry. 2023 Mar 10;23(1):156. doi: 10.1186/s12888-022-04434-9.

Abstract

Background: To determine the association between sleep disorders and Triglyceride glucose index.

Methods: A cross-sectional analysis of the 2005 to 2008 National Health and Nutrition Examination Survey (NHANES) was performed. The 2005 to 2008 NHANES national household survey for adults ≥ 20 years was examined for the sleep disorders.TyG index: ln [triglyceride (mg/ dL) × fasting blood glucose (mg/dL)/2].Multivariable logistic and linear regression models were used to explore the association between the TyG index and sleep disorders.

Results: A total of 4,029 patients were included. Higher TyG index is significantly associated with elevated sleep disorders in U.S. adults. TyG was moderately correlated with HOMA-IR (Spearman r = 0.51). TyG was associated with higher odds of sleep disorders(adjusted OR [aOR],1.896; 95% CI, 1.260 2.854), Sleep apnea (aOR, 1.559; 95% CI, 0.660 3.683), Insomnia(aOR, 1.914;95% CI, 0.531 6.896), and Restless legs (aOR, 7.759; 95% CI,1.446 41.634).

Conclusions: In this study, our result shown that population with higher TyG index are significantly more likely to have sleep disorders in U.S. adults.

Keywords: HOMA-IR; NHANES; Sleep disorders; Triglyceride glucose index.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biomarkers
  • Blood Glucose
  • Cross-Sectional Studies
  • Glucose*
  • Humans
  • Insulin Resistance*
  • Nutrition Surveys
  • Risk Factors
  • Triglycerides

Substances

  • Glucose
  • Blood Glucose
  • Triglycerides
  • Biomarkers