Is the Prevalence of Vitamin D deficiency in Patients with Temporomandibular Disorder Higher than Healthy Control Group?

J Maxillofac Oral Surg. 2022 Dec;21(4):1205-1208. doi: 10.1007/s12663-021-01522-3. Epub 2021 Feb 18.

Abstract

Purpose: Vitamin D plays an essential role in subchondral bone, cartilage, and periarticular muscle. This study aims to assess the prevalence of vitamin D deficiency in temporomandibular disorder (TMD) patients.

Materials and methods: This is a cross-sectional study. Subjects were assigned into two groups based on having signs and symptoms of TMD: Group 1: subjects had TMD, and group 2 healthy group (control group). The serum level of vitamin D was measured in the two groups. The independent t test was used to compare the serum level of vitamin D between the study and control groups.

Results: One hundred ten subjects were studied into two groups (55 subjects in each group). The mean serum level of vitamin D was 18.13 ± 6.38 ng/mL in the study group and 31.83 ± 7.00 ng/mL in the control group. Analysis of the data demonstrated a significant difference in the mean serum level of vitamin D between the study and control groups (p = 0.001).

Conclusion: It seems the serum level of vitamin D is lower in TMD patients than in the healthy control group.

Keywords: Pain; Temporomandibular joint; Temporomandibular joint disorders; Temporomandibular joint dysfunction syndrome; Vitamin D.