An Investigation of Latex Sensitivity and Respiratory Complaints in Workers in a Rubber-Based Material Manufacturing Industry

J Occup Environ Med. 2023 Jun 1;65(6):e378-e383. doi: 10.1097/JOM.0000000000002830. Epub 2023 Mar 9.

Abstract

Objective: To present study aimed to investigate the prevalence of latex sensitivity in a workplace that produced rubber-based vehicle seals.

Method: The serum latex-specific IgE levels, respiratory complaints, PFT, serum interleukin (IL)-4, IL-5, IL-8, IL-10, IL-13 levels of all male workers (n = 108) exposed to latex in the workplace, which produced rubber seals, were compared with the control group (n = 52).

Results: The rates of latex-specific IgE >0.10 kU/L in the workers and control group were 12.3% and 4.1%, respectively ( P = 0.147). There was no difference in IL-4, IL-5, IL-10, and IL-13 levels between latex-specific IgE-positive, and -negative participants.

Conclusion: Latex sensitivity was higher in workers who used rubber as a raw material than in the control group but it was not statistically significant.

MeSH terms

  • Humans
  • Immunoglobulin E
  • Interleukin-10
  • Interleukin-13
  • Interleukin-5
  • Latex / adverse effects
  • Latex Hypersensitivity* / epidemiology
  • Male
  • Manufacturing Industry
  • Rubber*

Substances

  • Rubber
  • Latex
  • Interleukin-10
  • Interleukin-13
  • Interleukin-5
  • Immunoglobulin E