Portal vein thrombosis (PVT) is one of the common complications of cirrhosis, which induces or aggravates ascites and upper gastrointestinal bleeding and even impacts the difficulty of liver transplantation by raising portal pressure, hence deteriorating the prognosis of patients. With the revelation of PVT-related research findings in recent years, the recognition of its mechanism and clinical risks has deepened. This article reviews the latest progress in PVT formation mechanisms and treatment strategies to improve clinicians' recognition of the pathogenesis and aid in formulating reasonable prevention and treatment.
门静脉血栓（PVT）是肝硬化常见并发症之一，通过升高门静脉压力，诱发或加重腹水、上消化道出血，甚至增加肝移植难度，影响患者预后。近年来，随着PVT相关研究结果公布，对其机制和临床危害认识不断深入。现就PVT形成机制与治疗策略的最新进展进行综述，以期提升临床医师对PVT发病机制的认识，辅助制定合理防治策略。.