Immunization is one the greatest prevention tools in the skillset of the general pediatrician. Ensuring that all patients, particularly adolescents and young adults, have the opportunity and access to age-appropriate vaccines should be an integral part of pediatric practice. Equitable immunization access and allocation should be afforded to adolescents and young adults to foster the health and well-being of America's next generation. This article will focus on select inequities that create health disparities disproportionately affecting adolescents and young adults of color. We seek to highlight inequities in adolescents and young adult vaccination and explore strategies for improving equity among this unique group. [Pediatr Ann. 2023;52(3):e102-e105.].