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Grants and funding
This work was supported by the Chinese National Key Technology Research and Development Program, Ministry of Science and Technology (2017YFC0907601, 2017YFC0907602), Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (2019-I2M-2-008), and Beijing Municipal Science and Technology Commission (No. Z201100005520023, Z201100005520027). The funding body had no role in data collection, data analysis, decision to publish, or writing the manuscript.