Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure

Risa Minamidate; Tetsuya Toyono; Yuichi Asahina; Sho Yamazawa; Takashi Miyai

doi:10.1016/j.ajoc.2023.101819

Corneal keloid caused by persistent atopic eye disease and chronic eyelid closure

Am J Ophthalmol Case Rep. 2023 Feb 15:30:101819. doi: 10.1016/j.ajoc.2023.101819. eCollection 2023 Jun.

Authors

Risa Minamidate^{1

2}, Tetsuya Toyono¹, Yuichi Asahina^{1

3}, Sho Yamazawa³, Takashi Miyai¹

Affiliations

¹ Department of Ophthalmology, The University of Tokyo Hospital, Tokyo, Japan.
² Department of Ophthalmology, Kanto Rosai Hospital, Kanagawa, Japan.
³ Department of Pathology, The University of Tokyo Hospital, Tokyo, Japan.

Abstract

Purpose: This report aimed to present a case of corneal fibrosis with prolonged atopic blepharitis caused by psychological resistance to steroid treatment.

Observations: A 49-year-old woman presented with atopic dermatitis and a history of panic attack and autism spectrum disorder. The upper and lower eyelid margins of her right eye became adherent, and the eyelid remained closed for several years due to refusal of steroid treatment and aggravation of blepharitis. During the initial examination, a lesion with elevated white opacity on the corneal surface was observed. Subsequently, superficial keratectomy was performed. The histopathological findings were indicative of corneal keloid.

Conclusions and importance: Persistent atopic ocular surface inflammation and prolonged eyelid closure resulted in the formation of a corneal keloid.

Keywords: Atopic blepharitis; Corneal fibrosis; Corneal keloid; Keratectomy.

Publication types

Case Reports