[Ultrasonographic features of retinal pigment epithelial adenoma]

Zhonghua Yan Ke Za Zhi. 2023 Mar 11;59(3):181-186. doi: 10.3760/cma.j.cn112142-20220803-00382.
[Article in Chinese]

Abstract

Objective: To investigate the ultrasonographic features of retinal pigment epithelium (RPE) adenoma. Methods: It was a retrospective case series study. The clinical clata of 15 patients (15 eyes) with pathologically confirmed RPE adenoma after local resection of intraocular tumor was collected at Beijing Tongren Hospital, Capital Medical University from November 2013 to October 2019. The general conditions of the patients and the location, size, shape, internal echo features of the lesions in the ocular ultrasound sonogram were analyzed, and the blood flow in the lesions was checked by color Doppler flow imaging (CDFI). Results: Of all the patients included in the study, 7 were male and 8 were female. Their age ranged from 25 to 58 years, with a mean age of (45.7±10.2) years. The most common symptom was vision loss or blurred vision (11 cases). Other symptoms included dark shadows or obscuration in front of the eyes (3 cases) and no symptoms (1 case). A history of previous ocular trauma was present in one case, and the rest of the patients had no history of ocular trauma.The location of tumor growth is scattered. The ultrasonographic features were as follows: the average maximum basal diameter was (8.07±2.75) mm and the average height was (4.02±1.81) mm; the ultrasonographic features mostly demonstrated abruptly elevated dome-shaped echo (6 cases); the lesion edge was not smooth, the internal echo was medium or low, and there could be hollow features (2 cases), with no choroidal depression; and the blood flow signal could be seen in the CDFI lesion, which could lead to retinal detachment and vitreous opacification. Conclusion: The ultrasound imaging features of RPE adenomas mostly demonstrate abruptly elevated dome-shaped echo, unsmooth lesion edge, with no choroidal depression, which may provide valuable evidence for clinical diagnosis and differentiation.

目的: 探讨视网膜色素上皮(RPE)腺瘤的超声影像特征。 方法: 回顾性病例系列研究。收集2013年11月至2019年10月首都医科大学附属北京同仁医院收治且眼内肿瘤局部切除手术后经组织病理学检查证实为RPE腺瘤15例(15只眼)患者的临床资料,分析患者的一般情况及眼部超声影像图中肿瘤的位置、大小、形态、内部回声以及彩色多普勒血流图(CDFI)检查的肿瘤内血流情况。 结果: 15例患者中,男性7例、女性8例;年龄(45.7±10.2)岁,范围25~58岁。出现最多的症状是视力下降或视物模糊(11例),其他包括眼前黑影或遮挡感(3例)和无症状(1例);1例患者存在既往眼部外伤史,其余患者均没有明确眼部外伤史。RPE腺瘤生长部位分散。超声检查示肿瘤最大基底径(8.07±2.75)mm,高度(4.02±1.81)mm;形态多为陡峭隆起的圆顶形(6例),边缘不光滑,内部呈中或低回声,其中2例肿瘤内部可见挖空征;无脉络膜凹陷;可继发视网膜脱离及玻璃体混浊;CDFI检查示肿瘤内可见血流信号。 结论: RPE腺瘤的超声影像特征是多为陡峭隆起的圆顶形态、边缘不光滑、无脉络膜凹陷,可为临床诊断及鉴别诊断提供参考。.

Publication types

  • English Abstract

MeSH terms

  • Adenoma*
  • Adult
  • Choroid
  • Eye Injuries*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies