68 Ga-DOTATOC PET/CT Imaging of a Muscular Solitary Fibrous Tumor

Clin Nucl Med. 2023 May 1;48(5):e228-e229. doi: 10.1097/RLU.0000000000004615. Epub 2023 Mar 1.

Abstract

A 73-year-old woman was referred for 68 Ga-DOTATOC PET/CT staging of a grade 2 pancreatic neuroendocrine tumor, which showed the primary pancreatic tumor, liver metastases, one left pleural metastasis, and high uptake in a mass of the right triceps brachii muscle. Two years before, she underwent 18 F-FDG PET/CT and 111 In-pentetreotide scan, respectively, with low and high uptake of each radiotracer in the triceps mass. Histopathological analysis revealed a solitary fibrous tumor. Immunohistochemistry showed no staining for SSTR-2 and SSTR-5, suggesting tumor overexpression of another somatostatin receptor. This case highlighted a potential pitfall on 68 Ga-DOTATOC PET/CT.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Female
  • Hemangiopericytoma*
  • Humans
  • Neuroendocrine Tumors* / diagnostic imaging
  • Neuroendocrine Tumors* / pathology
  • Octreotide
  • Organometallic Compounds*
  • Pancreatic Neoplasms* / pathology
  • Positron Emission Tomography Computed Tomography / methods
  • Positron-Emission Tomography / methods
  • Receptors, Somatostatin
  • Solitary Fibrous Tumors*

Substances

  • Edotreotide
  • Octreotide
  • Receptors, Somatostatin
  • Gallium-68
  • Organometallic Compounds