Neural Plasticity in Sensorimotor Brain-Machine Interfaces

Annu Rev Biomed Eng. 2023 Jun 8:25:51-76. doi: 10.1146/annurev-bioeng-110220-110833. Epub 2023 Feb 28.

Abstract

Brain-machine interfaces (BMIs) aim to treat sensorimotor neurological disorders by creating artificial motor and/or sensory pathways. Introducing artificial pathways creates new relationships between sensory input and motor output, which the brain must learn to gain dexterous control. This review highlights the role of learning in BMIs to restore movement and sensation, and discusses how BMI design may influence neural plasticity and performance. The close integration of plasticity in sensory and motor function influences the design of both artificial pathways and will be an essential consideration for bidirectional devices that restore both sensory and motor function.

Keywords: brain–machine interface; learning; motor; neural circuits; plasticity; sensory.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain
  • Brain-Computer Interfaces*
  • Humans
  • Learning
  • Movement
  • Neuronal Plasticity