Precision mapping and transcranial magnetic stimulation of individual-specific functional brain networks in humans

STAR Protoc. 2023 Mar 17;4(1):102118. doi: 10.1016/j.xpro.2023.102118. Epub 2023 Feb 14.

Abstract

Spatial targeting in transcranial magnetic stimulation protocols does not typically account for the idiosyncratic functional organization of individual human brains. Here, we provide a protocol for implementing targeted functional network stimulation (TANS), which accounts for each individual's unique functional neuroanatomy and cortical folding patterns. Using an example dataset, we describe how to create a head model and estimate the best coil placement and stimulation intensity to minimize off-target effects. For complete details on the use and execution of this protocol, please refer to Lynch et al. (2022).1.

Keywords: Bioinformatics; Clinical Protocol; Cognitive Neuroscience; Neuroscience.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain / physiology
  • Brain Mapping* / methods
  • Head
  • Humans
  • Transcranial Magnetic Stimulation* / methods