Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication

Elles J Reimerink; Daan W Huntjens; Lindsey G Pelkmans; Jan-Willem H J Geerts; Eric J F Franssen

doi:10.3390/toxics11020196

Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication

Toxics. 2023 Feb 20;11(2):196. doi: 10.3390/toxics11020196.

Authors

Elles J Reimerink¹, Daan W Huntjens², Lindsey G Pelkmans¹, Jan-Willem H J Geerts¹, Eric J F Franssen²

Affiliations

¹ Department of Intensive Care, OLVG Hospital, 1061 AE Amsterdam, The Netherlands.
² Department of Clinical Pharmacy, OLVG Hospital, 1061 AE Amsterdam, The Netherlands.

Abstract

Here we describe the case of a potentially lethal caffeine intoxication after the reported ingestion of 10 g of caffeine. Due to hemodynamic instability with tachycardia and hypertension with an insufficient effect of continuous labetalol infusion, the patient was started on continuous veno-venous haemodialysis (CVVHD). After successful treatment for 15 h, CVVHD could be discontinued, and the patient was discharged home the next day. This case report is the first to report the use of CVVHD as a haemodialysis modality in the case of caffeine intoxication and illustrate the effect on caffeine clearance. We stress the importance of an early recognition of caffeine intoxication, so that haemodialysis can be considered in the case of a potentially lethal intoxication.

Keywords: caffeine clearance; caffeine intoxication; continuous veno-venous haemodialysis.

Publication types

Case Reports

Grants and funding

This research received no external funding.