3D printing for personalised medicines: implications for policy and practice

Int J Pharm. 2023 Mar 25:635:122785. doi: 10.1016/j.ijpharm.2023.122785. Epub 2023 Feb 26.

Abstract

The current healthcare dynamic has shifted from one-size-fits-all to patient-centred care, with our increased understanding of pharmacokinetics and pharmacogenomics demanding a switch to more individualised therapies. As the pharmaceutical industry remains yet to succumb to the push of a technological paradigm shift, pharmacists lack the means to provide completely personalised medicine (PM) to their patients in a safe, affordable, and widely accessible manner. As additive manufacturing technology has already established its strength in producing pharmaceutical formulations, it is necessary to next consider methods by which this technology can create PM accessible from pharmacies. In this article, we reviewed the limitations of current pharmaceutical manufacturing methods for PMs, three-dimensional (3D) printing techniques that are most beneficial for PMs, implications of bringing this technology into pharmacy practice, and implications for policy surrounding 3D printing techniques in the manufacturing of PMs.

Keywords: 3D printing; Additive manufacturing; Compounding; Personalised medicine; Pharmacy practice; Policy.

Publication types

  • Review

MeSH terms

  • Drug Industry / methods
  • Humans
  • Pharmaceutical Preparations
  • Precision Medicine*
  • Printing, Three-Dimensional
  • Technology, Pharmaceutical* / methods

Substances

  • Pharmaceutical Preparations