Exclusion of latecomers yields a patchwork of viral subpopulations within hosts

PLoS Biol. 2023 Feb 9;21(2):e3001994. doi: 10.1371/journal.pbio.3001994. eCollection 2023 Feb.

Abstract

Viruses arriving late to an individual cell are blocked from replicating, an effect called superinfection exclusion. A study in PLOS Biology indicates that this exclusion at the level of individual cells gives rise to a heterogenous landscape of infection within a host.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Humans
  • Orthomyxoviridae*
  • Superinfection*