Progress of new-onset diabetes after liver and kidney transplantation

Zhen Zhang; Jianyun Sun; Meng Guo; Xuemin Yuan

doi:10.3389/fendo.2023.1091843

Progress of new-onset diabetes after liver and kidney transplantation

Front Endocrinol (Lausanne). 2023 Feb 8:14:1091843. doi: 10.3389/fendo.2023.1091843. eCollection 2023.

Authors

Zhen Zhang¹, Jianyun Sun², Meng Guo³, Xuemin Yuan²

Affiliations

¹ Department of Urology, The People's Hospital of Linyi, Linyi, Shandong, China.
² Department of Gastroenterology, The People's Hospital of Linyi, Linyi, Shandong, China.
³ National Key Laboratory of Medical Immunology &Institute of Immunology, Navy Medical University, Shanghai, China.

Abstract

Organ transplantation is currently the most effective treatment for end-stage organ failure. Post transplantation diabetes mellitus (PTDM) is a severe complication after organ transplantation that seriously affects the short-term and long-term survival of recipients. However, PTDM is often overlooked or poorly managed in its early stage. This article provides an overview of the incidence, and pathogenesis of and risk factors for PTDM, aiming to gain a deeper understanding of PTDM and improve the quality of life of recipients.

Keywords: hyperglycemia; insulin resistance; kidney transplantation; liver transplantation; post transplantation diabetes mellitus.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Diabetes Mellitus* / epidemiology
Diabetes Mellitus* / etiology
Humans
Kidney Transplantation* / adverse effects
Liver
Quality of Life
Risk Factors

Grants and funding

This study was supported by A Special Sup-portive Program for Organ transplantation by COTDF (2019JYJH11) and Linyi key research and development Program (2022YX0018).