Transition Metal Complexes of Thiosemicarbazides, Thiocarbohydrazides, and Their Corresponding Carbazones with Cu(I), Cu(II), Co(II), Ni(II), Pd(II), and Ag(I)-A Review

Ashraf A Aly; Elham M Abdallah; Salwa A Ahmed; Mai M Rabee; Stefan Bräse

doi:10.3390/molecules28041808

Transition Metal Complexes of Thiosemicarbazides, Thiocarbohydrazides, and Their Corresponding Carbazones with Cu(I), Cu(II), Co(II), Ni(II), Pd(II), and Ag(I)-A Review

Molecules. 2023 Feb 14;28(4):1808. doi: 10.3390/molecules28041808.

Authors

Ashraf A Aly¹, Elham M Abdallah¹, Salwa A Ahmed¹, Mai M Rabee¹, Stefan Bräse^{2

3}

Affiliations

¹ Chemistry Department, Faculty of Science, El-Minia University, Minia 61519, Egypt.
² Institute of Organic Chemistry, Karlsruher Institut fur Technologie, 76131 Karlsruhe, Germany.
³ Institute of Biological and Chemical Systems (IBCS-FMS), Karlsruhe Institute of Technology, Eggenstein Leopoldshafen, 76344 Karlsruhe, Germany.

Abstract

This review focuses on some interesting and recent applications of transition metals towards the complexation of thiosemicarbazides, thiocarbohydrazides, and their corresponding carbazones. We started the review with a description of the chosen five metals, including Cu[Cu(I), Cu(II], Co(II), Ni(II), Pd(II), and Ag(I) and their electronic configurations. The stability of the assigned complexes was also discussed. We shed light on different routes describing the synthesis of these ligands. We also reported on different examples of the synthesis of Cu(I), Cu(II), Co(II), Ni(II), Ag(I), and Pd(II) of thiosemicarbazide and thiocarbohydrazide complexes (until 2022). This review also deals with a summary of the fruitful use of metal complexes of thiosemicarbazones and thiocarbazones ligands in the field of catalysis. Finally, this recent review focuses on the applications of these complexes related to their biological importance.

Keywords: Co(II); Cu(I); Cu(II); Ni(II); Pd(II) and Ag(I) complexes; biological activity; catalysis; synthesis; thiosemicarbazides; thiosemicarbazones.

Publication types

Review

MeSH terms

Coordination Complexes*
Copper
Hydrazines
Ligands
Transition Elements*

Substances

Coordination Complexes
thiocarbohydrazide
thiosemicarbazide
Ligands
Hydrazines
Transition Elements
Copper

Grants and funding

This research received no external funding.