Diabetic Muscle Infarction-A Rare Diabetic Complication: Literature Review and Case Report

Int J Environ Res Public Health. 2023 Feb 15;20(4):3390. doi: 10.3390/ijerph20043390.

Abstract

We present a case of a 31-year-old patient with type 1 diabetes diagnosed at the age of 6. Diabetes is complicated with neuropathy, retinopathy, and nephropathy. He has been admitted to the diabetes ward due to inadequate diabetes control. Gastroscopy and abdominal CT were performed, and gastroparesis was confirmed as an explanation for postprandial hypoglycemia. During hospitalization, the patient reported sudden pain localized on the lateral, distal part of his right thigh. The pain occurred at rest and was aggravated by movement. Diabetic muscle infarction (DMI) is a rare complication of long-lasting, uncontrolled diabetes mellitus. It usually occurs spontaneously, without any previous infection or trauma, and is often misdiagnosed clinically as an abscess, neoplasm, or myositis. DMI patients suffer from pain and swelling of the affected muscles. Radiological examinations, including MRI, CT, and USG, are most important for the diagnosis, assessing the extent of involvement and differentiating DMI from other conditions. However, sometimes a biopsy and histopathological examination are necessary. The optimal treatment has still not been determined. There is also a potential risk of DMI recurrence.

Keywords: diabetic microangiopathy; diabetic muscle infarction; insulin-dependent diabetes mellitus complication.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diabetes Complications* / complications
  • Diabetes Mellitus, Type 1* / complications
  • Humans
  • Infarction / pathology
  • Magnetic Resonance Imaging / adverse effects
  • Male
  • Muscle, Skeletal / pathology
  • Pain / complications

Grants and funding

This research received no external funding.