Gender Differences in Determinants of the Components of the Frailty Phenotype among Older Adults in India: Findings from LASI Wave-1

Int J Environ Res Public Health. 2023 Feb 9;20(4):3055. doi: 10.3390/ijerph20043055.

Abstract

This study examines the gender-specific determinants of the components of frailty in a community-dwelling setting in India. Using data from the Longitudinal Ageing Study in India (LASI) Wave-1, this study employed 30,978 (14,885 male and 16,093 female) older adults (aged 60+) to fulfil the study objective. The modified Fried frailty phenotype criteria defines frailty by the five components: exhaustion, weak grip strength, slow walking speed, unintentional weight loss, and low physical activity. The result showed grip strength (79.1%) as the most discriminant component among males, and physical activity (81.6%) as the most discriminant component among females. The results also indicated that grip strength (male: 98.0%, female: 93.5%) and physical activity (male: 94.8%, female: 96.9%) showed a sensitivity of more than 90%, which appears to be a good indicator of frailty. Combining this dual marker increased the accuracy to 99.97% among male and 99.98% among female samples. The findings suggested adding grip strength and physical activity as a proxy measure of frailty, which can increase the precision of screening without a large additional investment of time, training, or cost.

Keywords: community-dwelling; frailty phenotype; handgrip strength; older people; physical activity.

MeSH terms

  • Aged
  • Aging
  • Female
  • Frail Elderly
  • Frailty* / diagnosis
  • Geriatric Assessment / methods
  • Humans
  • Independent Living
  • Male
  • Phenotype
  • Sex Factors

Grants and funding

This research received no external funding.