myBeST-A Web-Based Survival Prognostic Tool for Women with Breast Cancer in Malaysia: Development Process and Preliminary Validation Study

Mohd Nasrullah Nik Ab Kadir; Suhaily Mohd Hairon; Najib Majdi Yaacob; Siti Norbayah Yusof; Kamarul Imran Musa; Maya Mazuwin Yahya; Seoparjoo Azmel Mohd Isa; Muhammad Hafizuddin Mamat Azlan; Imi Sairi Ab Hadi

doi:10.3390/ijerph20042985

myBeST-A Web-Based Survival Prognostic Tool for Women with Breast Cancer in Malaysia: Development Process and Preliminary Validation Study

Int J Environ Res Public Health. 2023 Feb 8;20(4):2985. doi: 10.3390/ijerph20042985.

Authors

Mohd Nasrullah Nik Ab Kadir¹, Suhaily Mohd Hairon¹, Najib Majdi Yaacob², Siti Norbayah Yusof³, Kamarul Imran Musa¹, Maya Mazuwin Yahya⁴, Seoparjoo Azmel Mohd Isa⁵, Muhammad Hafizuddin Mamat Azlan⁶, Imi Sairi Ab Hadi⁷

Affiliations

¹ Department of Community Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
² Biostatistics and Research Methodology Unit, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
³ Malaysian National Cancer Registry Department, National Cancer Institute, Ministry of Health Malaysia, Putrajaya 62250, Federal Territory of Putrajaya, Malaysia.
⁴ Department of Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
⁵ Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
⁶ Hospital Sibu, Ministry of Health Malaysia, Sibu 96000, Sarawak, Malaysia.
⁷ Breast and Endocrine Surgery Unit, Department of Surgery, Hospital Raja Perempuan Zainab II, Ministry of Health Malaysia, Kota Bharu 15586, Kelantan, Malaysia.

Abstract

Women with breast cancer are keen to know their predicted survival. We developed a new prognostic model for women with breast cancer in Malaysia. Using the model, this study aimed to design the user interface and develop the contents of a web-based prognostic tool for the care provider to convey survival estimates. We employed an iterative website development process which includes: (1) an initial development stage informed by reviewing existing tools and deliberation among breast surgeons and epidemiologists, (2) content validation and feedback by medical specialists, and (3) face validation and end-user feedback among medical officers. Several iterative prototypes were produced and improved based on the feedback. The experts (n = 8) highly agreed on the website content and predictors for survival with content validity indices ≥ 0.88. Users (n = 20) scored face validity indices of more than 0.90. They expressed favourable responses. The tool, named Malaysian Breast cancer Survival prognostic Tool (myBeST), is accessible online. The tool estimates an individualised five-year survival prediction probability. Accompanying contents were included to explain the tool's aim, target user, and development process. The tool could act as an additional tool to provide evidence-based and personalised breast cancer outcomes.

Keywords: Malaysian women; breast cancer; eHealth; prognosis; web-based tool.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Breast
Breast Neoplasms*
Female
Humans
Internet
Malaysia
Prognosis

Grants and funding

This research was funded by the Seed Money for Research and Postgraduate Studies Development Incentive Fund (Tabung Insentif Pembangunan Pengajian Siswazah, TIPPS), grant number USM/PPSP/PG/2.0/012 (21) from the School of Medical Sciences, Universiti Sains Malaysia. The article publication fee (APC) was funded by the School of Medical Sciences, Universiti Sains Malaysia.