Fibromatosis-Like Metaplastic Carcinoma: A Triple-Negative Breast Cancer with Clinically Indolent Behavior

Khoa Hong Pham; Chu Van Nguyen; Tu Anh Do; Han Thi Pham; Kien Hung Do; Duc Thanh Le

doi:10.1159/000526535

Fibromatosis-Like Metaplastic Carcinoma: A Triple-Negative Breast Cancer with Clinically Indolent Behavior

Case Rep Oncol. 2022 Sep 26;15(3):816-826. doi: 10.1159/000526535. eCollection 2022 Sep-Dec.

Authors

Khoa Hong Pham¹, Chu Van Nguyen^{1

2}, Tu Anh Do¹, Han Thi Pham¹, Kien Hung Do¹, Duc Thanh Le¹

Affiliations

¹ aNational Cancer Hospital, Hanoi, Vietnam.
² bHanoi Medical University, Hanoi, Vietnam.

Abstract

Fibromatosis-like metaplastic carcinoma is a special variant of spindle cell carcinoma, a type of metaplastic carcinomas. It has a favorable prognosis, unlike other metaplastic carcinomas, with a particular clinical behavior characterized by frequent local recurrence, the meager potential for axillary lymph nodes, and distant metastases. We presented the case of a 51-year-old female with a large mass on the left breast, which was successfully removed by surgical resection. The pathological diagnosis was fibromatosis-like metaplastic carcinoma with the help of morphology and immunohistochemistry adjustment.

Keywords: Fibromatosis-like metaplastic carcinoma; Pathology; Prognosis; Treatment.

Publication types

Case Reports

Grants and funding

The authors received no financial support for the research, authorship, and/or publication of this article.