We study the problem of misalignment aberration analysis and correction of the two-mirror telescopes with stop on the secondary mirror. The variation law of the system's aberration field is analyzed with nodal aberration theory when the primary mirror with an astigmatic figure error is misaligned. The analytic expression among the system wave aberration, misalignments, and astigmatism figure error is given, and the correction model of system misalignment aberration is established. The simulation experiment shows that the relative error of the prediction of system misalignment coma and astigmatism based on this model is less than 4.1%.