PROX1 restrains ferroptosis via SCD transcription activation in colorectal cancer

Ruoxin Zhang; Dakui Luo; Zezhi Shan; Yufei Yang; Yi Qin; Qingguo Li; Xinxiang Li

doi:10.3724/abbs.2023027

PROX1 restrains ferroptosis via SCD transcription activation in colorectal cancer

Acta Biochim Biophys Sin (Shanghai). 2023 Feb 23;55(4):691-694. doi: 10.3724/abbs.2023027.

Authors

Ruoxin Zhang^{1

2}, Dakui Luo^{1

2}, Zezhi Shan^{1

2}, Yufei Yang^{1

2}, Yi Qin³, Qingguo Li^{1

2}, Xinxiang Li^{1

2}

Affiliations

¹ Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
² Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
³ Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.

No abstract available

MeSH terms

Colorectal Neoplasms* / genetics
Ferroptosis*
Homeodomain Proteins / genetics
Humans
Transcription Factors / metabolism
Transcriptional Activation

Substances

Transcription Factors
Homeodomain Proteins

Grants and funding

This work was supported by the grants from the National Natural Science Foundation of China (Nos. 81972260 and 82103259), Shanghai Municipal Natural Science Foundation (No. 21ZR1414400), and Shanghai Medical Innovation Research Project (No. 22Y11907600).