Eat for better cognition in older adults at risk for Alzheimer's disease

Yuye Wang; Xiaoqian Niu; Dantao Peng

doi:10.1016/j.nut.2022.111969

Eat for better cognition in older adults at risk for Alzheimer's disease

Nutrition. 2023 May:109:111969. doi: 10.1016/j.nut.2022.111969. Epub 2023 Jan 11.

Authors

Yuye Wang¹, Xiaoqian Niu², Dantao Peng³

Affiliations

¹ China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
² Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China.
³ China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Peking University China-Japan Friendship School of Clinical Medicine, Beijing, China. Electronic address: pengdantao2000@163.com.

PMID: 36801704
DOI: 10.1016/j.nut.2022.111969

Abstract

Alzheimer's disease is a worldwide public health problem. However, the treatment method and treatment effects are limited. The stages of preclinical Alzheimer's disease are thought to be a better intervention period. Thus, in this review, food is given focus and the intervention stage put forward. We summarized the role of diet, nutrient supplementation, and microbioecologics in cognitive decline and found that interventions such as modified Mediterranean-ketogenic diet, nuts, vitamin B, and Bifidobacterium breve A1 are beneficial to cognition protection. Eating, rather than just taking medicine, is suggested to be an effective treatment method for older adults at risk for Alzheimer's disease.

Keywords: Cognition; Eating; Mild cognitive impairment; Nutrition; Subjective memory impairment.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Alzheimer Disease* / prevention & control
Cognition
Cognitive Dysfunction* / etiology
Cognitive Dysfunction* / prevention & control
Diet, Mediterranean*
Humans
Vitamin B Complex*

Substances

Vitamin B Complex