Biological effects of the frequent application of a copper-containing fungicide on the fruit fly Drosophila melanogaster

Res Sq [Preprint]. 2023 Feb 9:rs.3.rs-2556997. doi: 10.21203/rs.3.rs-2556997/v1.

Abstract

The increased consumption of pesticides has an environmental impact due to the dispersion of minerals. Bordasul® is a commonly used fungicide composed of 20% Cu, 10% sulfur, and 3.0% calcium to correct its deficiency in plants. The evaluation of fungicide effects in vivo models is designed to assess their impact on the environment more broadly. Drosophila melanogaster offers a unique model due to its ease of handling and maintenance. Here, the effects of Bordasul® were investigated, addressing the development, survival, and behavior of flies. Our findings showed that exposure to Bordasul® prevented the development of flies (p < 0.01). In addition to causing a significant reduction in memory retention (p < 0.05) and locomotion capacity (p < 0.001). Although fungicides are necessary to satisfy the world's food demand, we conclude that Bordasul® is highly toxic, and that safer media, such as biofertilizers, must be developed as effective alternatives.

Keywords: behavior; environment; memory retention; pesticides; toxicity.

Publication types

  • Preprint