Impact of a Documented Penicillin Allergy on Antibiotic Selection in Pediatric Patients With Osteomyelitis

Pediatr Infect Dis J. 2023 May 1;42(5):e140-e142. doi: 10.1097/INF.0000000000003863. Epub 2023 Feb 8.

Abstract

Penicillin allergy labels are common in hospitalized patients, and there is a frequent misconception that these patients cannot receive cephalosporins. Through retrospective review, we found that patients with reported penicillin allergies were significantly less likely to receive first-line therapy for acute hematogenous osteomyelitis.

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Child
  • Drug Hypersensitivity*
  • Humans
  • Hypersensitivity* / drug therapy
  • Osteomyelitis* / drug therapy
  • Penicillins / adverse effects
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents
  • Penicillins