COVID-19 Breakthrough Infection Among Vaccinated Population in the United Arab Emirates

J Epidemiol Glob Health. 2023 Mar;13(1):67-90. doi: 10.1007/s44197-023-00090-8. Epub 2023 Feb 16.

Abstract

Background: Despite significant efforts to contain the Coronavirus Disease 2019 (COVID-19) pandemic through mass vaccination, numerous nations throughout the world have recorded breakout infections. The incidence and severity of COVID-19 breakthrough infections in the United Arab Emirates (UAE) remain unknown despite extensive COVID-19 vaccine coverage. The goal of this research is to establish the characteristics of COVID-19 breakthrough infections in the UAE's vaccinated population.

Methods: Between February and March 2022, we conducted a descriptive cross-sectional study in the UAE with 1533 participants to examine the characteristics of COVID-19 breakthrough infection among the vaccinated population.

Results: The vaccination coverage was 97.97%, and the COVID-19 breakthrough infection rate was 32.1%, requiring hospitalization in 7.7% of cases. The bulk of the 492 COVID-19 breakthrough infections reported was among young adults (67%), with the majority experiencing mild to moderate symptoms (70.7%) or remaining asymptomatic (21.5%).

Conclusions: COVID-19 breakthrough infection were reported in younger age, male sex, non-healthcare professions, vaccination with inactivated whole virus vaccine (Sinopharm), and not receiving a booster dose. Information on breakthrough infection in the UAE might influence public health decisions and motivate measures such as providing additional booster doses of the vaccines to the people.

Keywords: Breakthrough infections; COVID-19; Covid vaccine; Pfizer-BioNTech; Sinopharm BBIBP-CorV; UAE.

MeSH terms

  • Breakthrough Infections
  • COVID-19 Vaccines
  • COVID-19*
  • Cross-Sectional Studies
  • Humans
  • Male
  • United Arab Emirates
  • Young Adult

Substances

  • COVID-19 Vaccines

Supplementary concepts

  • COVID-19 breakthrough infections