Common Noninfectious Complications Following Lung Transplantation

Harpreet Singh Grewal; Tany Thaniyavarn; Selim M Arcasoy; Hilary J Goldberg

doi:10.1016/j.ccm.2022.11.001

Common Noninfectious Complications Following Lung Transplantation

Clin Chest Med. 2023 Mar;44(1):179-190. doi: 10.1016/j.ccm.2022.11.001.

Authors

Harpreet Singh Grewal¹, Tany Thaniyavarn², Selim M Arcasoy³, Hilary J Goldberg²

Affiliations

¹ Lung Transplant Program, Columbia University, Irving Medical Center, 622 West 168th Street, PH 14E, Suite 104, New York, NY 10032, USA. Electronic address: hsg2138@cumc.columbia.edu.
² Lung Transplant Program, Brigham and Women's Hospital, 75 Francis Street, PBB Clinic 3, Boston, MA 02115, USA.
³ Lung Transplant Program, Columbia University, Irving Medical Center, 622 West 168th Street, PH 14E, Suite 104, New York, NY 10032, USA.

PMID: 36774163
DOI: 10.1016/j.ccm.2022.11.001

Abstract

According to the Scientific Registry of Transplant Recipients, both transplant volume and survival among lung transplant recipients are improving over time. However, the outcomes of lung transplantation remain challenged by multiple thoracic and extrathoracic complications. With improving lung transplant survival, patients experience prolonged exposure to chronic immunosuppressive agents that can lead to multiple infectious and noninfectious complications. This article focuses on most common noninfectious complications with significant clinical impact.

Keywords: Extrathoracic complications; Immunosuppression; Lung transplantation; Thoracic complications.

Publication types

Review

MeSH terms

Heart Transplantation* / adverse effects
Humans
Immunosuppressive Agents
Lung Transplantation* / adverse effects
Postoperative Complications / etiology
Postoperative Complications / therapy
Time Factors

Substances

Immunosuppressive Agents