Traditional vs. Microfluidic Synthesis of ZnO Nanoparticles

Maria Leila Popa; Manuela Daniela Preda; Ionela Andreea Neacșu; Alexandru Mihai Grumezescu; Octav Ginghină

doi:10.3390/ijms24031875

Traditional vs. Microfluidic Synthesis of ZnO Nanoparticles

Int J Mol Sci. 2023 Jan 18;24(3):1875. doi: 10.3390/ijms24031875.

Authors

Maria Leila Popa¹, Manuela Daniela Preda¹, Ionela Andreea Neacșu^{1

2}, Alexandru Mihai Grumezescu^{1

3

4}, Octav Ginghină⁵

Affiliations

¹ Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania.
² National Research Center for Micro and Nanomaterials, University Politehnica of Bucharest, 060042 Bucharest, Romania.
³ Research Institute of the University of Bucharest-ICUB, University of Bucharest, 050657 Bucharest, Romania.
⁴ Academy of Romanian Scientists, Ilfov No. 3, 050044 Bucharest, Romania.
⁵ Faculty of Medicine, University of Medicine and Pharmacy Carol Davila from Bucharest, 37 Dionisie Lupu Street, District 2, 020021 Bucharest, Romania.

Abstract

Microfluidics provides a precise synthesis of micro-/nanostructures for various applications, including bioengineering and medicine. In this review article, traditional and microfluidic synthesis methods of zinc oxide (ZnO) are compared concerning particle size distribution, morphology, applications, reaction parameters, used reagents, and microfluidic device materials. Challenges of traditional synthesis methods are reviewed in a manner where microfluidic approaches may overcome difficulties related to synthesis precision, bulk materials, and reproducibility.

Keywords: challenges; microfluidics; nanoparticles; polydimethylsiloxane (PDMS); zinc oxide.

Publication types

Review

MeSH terms

Microfluidics / methods
Nanoparticles* / chemistry
Nanostructures* / chemistry
Reproducibility of Results
Zinc Oxide* / chemistry

Substances

Zinc Oxide

Grants and funding

This research received no external funding.