Introduction to the Special Issue "Skeletal Muscle Atrophy: Mechanisms at a Cellular Level"

Emanuela Zuccaro; Caterina Marchioretti; Marco Pirazzini; Maria Pennuto

doi:10.3390/cells12030502

Introduction to the Special Issue "Skeletal Muscle Atrophy: Mechanisms at a Cellular Level"

Cells. 2023 Feb 3;12(3):502. doi: 10.3390/cells12030502.

Authors

Emanuela Zuccaro^{1

2

3}, Caterina Marchioretti^{1

2

3}, Marco Pirazzini^{1

4}, Maria Pennuto^{1

2

3}

Affiliations

¹ Department of Biomedical Sciences (DBS), University of Padova, 35128 Padova, Italy.
² Veneto Institute of Molecular Medicine (VIMM), 35128 Padova, Italy.
³ Padova Neuroscience Centre (PNC), 35128 Padova, Italy.
⁴ Cir-Myo, Centro Interdipartimentale di Ricerca di Miologia, University of Padova, 35131 Padova, Italy.

Abstract

Skeletal muscle is the most abundant tissue in the body and requires high levels of energy to function properly. Skeletal muscle allows voluntary movement and body posture, which require different types of fiber, innervation, energy, and metabolism. Here, we summarize the contribution received at the time of publication of this Introductory Issue for the Special Issue dedicated to "Skeletal Muscle Atrophy: Mechanisms at a Cellular Level". The Special Issue is divided into three sections. The first is dedicated to skeletal muscle pathophysiology, the second to disease mechanisms, and the third to therapeutic development.

Keywords: atrogenes; cancer cachexia; muscle atrophy; muscle degeneration; muscle proteostasis and disuse; myopathies; neuromuscular disorder; neuromuscular paralysis; sarcopenia.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Humans
Muscle, Skeletal* / metabolism
Muscular Atrophy* / pathology

Grants and funding

This research was funded by Fondazione Telethon (GGP19128 to M.P. (Maria Pennuto)), Association Française Contre les Myopathies (22221 to M.P. (Maria Pennuto)), PROGRAM RARE DISEASES CNCCS-Scarl-Pomezia (to M.P. (Maria Pennuto)), Kennedy’s Disease Association Research Grant (U-GOV PIRA_EPPR19_01 to M.P. (Marco Pirazzini) and AWD00002349 to E.Z.), and the Fondazione Umberto Veronesi Fellowship (to E.Z.). The figures were created with BioRender.com (agreement number HY24YQV5E4; VS24YQDCCW).