Airborne levels of cadmium are correlated with urinary cadmium concentrations among young children living in the New York state city of Syracuse, USA

Dustin T Hill; Vikrant Jandev; Michael Petroni; Nader Atallah-Yunes; Kestas Bendinskas; Lynn S Brann; Kevin Heffernan; David A Larsen; James A MacKenzie; Christopher D Palmer; Patrick J Parsons; Brooks B Gump; Mary B Collins

doi:10.1016/j.envres.2023.115450

Airborne levels of cadmium are correlated with urinary cadmium concentrations among young children living in the New York state city of Syracuse, USA

Environ Res. 2023 Apr 15:223:115450. doi: 10.1016/j.envres.2023.115450. Epub 2023 Feb 9.

Authors

Affiliations

¹ Falk College of Sport and Human Dynamics, Department of Public Health, Syracuse University, Syracuse, NY, 13244, USA. Electronic address: dthill@syr.edu.
² Department of Chemistry, State University of New York College at Oswego, Oswego, NY, 13126, USA.
³ Graduate Program in Environmental Science, Center for Environmental Medicine and Informatics, SUNY College of Environmental Science and Forestry, Syracuse, NY, 13210, USA.
⁴ Division of Pediatric Cardiology, Department of Pediatrics, Upstate Medical University Hospital, Syracuse, NY, 13210, USA; Division of Pediatric Cardiology, Department of Pediatrics, Golisano Children's Hospital at the University of Rochester, Rochester, NY, 14642, USA.
⁵ Department of Nutrition and Food Studies, Syracuse University, Syracuse, NY, 13210, USA.
⁶ Department of Exercise Science, Syracuse University, Syracuse, NY, 13210, USA.
⁷ Falk College of Sport and Human Dynamics, Department of Public Health, Syracuse University, Syracuse, NY, 13244, USA.
⁸ Department of Biological Sciences, State University of New York College at Oswego, Oswego, NY, 13126, USA.
⁹ Laboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, 12237, USA; Department of Environmental Health Sciences, School of Public Health, University at Albany, Rensselaer, NY, 12144, USA.
¹⁰ Department of Environmental Studies, Environmental Health Program, Center for Environmental Medicine and Informatics, SUNY College of Environmental Science and Forestry, Syracuse, NY, 13210, USA.

Abstract

Air pollution is a serious public health issue with early childhood exposure being of high concern because of the greater risk that children might experience negative health outcomes. Industrial sources in and near communities are one potential path of exposure that children might face with greater levels of air pollution correlating with higher levels of toxicants detected in children. We compare estimated ambient air concentrations of Cadmium (Cd) to a cohort (n = 281) of 9 to 11-year old children during their early childhood years (0-5 years of age) in a mid-size city in Upstate New York. Levels of Cd air pollution are compared to children's urine-Cd levels. Urine has been shown to be a superior biomarker to blood for Cd exposure particularly for longer-term exposures. We find that participants who reside in households that faced greater Cd air pollution during the child's early years have higher urine-Cd levels. This association is stable and stronger than previously presented associations for blood-Cd. Findings support expanded use of air modelling data for risk screening to reduce the potential health burden that industrial pollution can have.

Keywords: Cadmium; Exposure; Industrial air pollution; Risk screening environmental indicators geographic microdata (RSEI-GM); Toxicants; Urine metal levels.

Publication types

Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

MeSH terms

Air Pollutants* / analysis
Air Pollution* / analysis
Cadmium
Child
Child, Preschool
Environmental Exposure / analysis
Environmental Pollution
Humans
New York City

Substances

Cadmium
Air Pollutants

Grants and funding

R01 ES023252/ES/NIEHS NIH HHS/United States