Reported here is an efficient and simple ether-directed iridium-catalyzed enantioselective C(sp3 )-H borylation of cyclopropanes. Various functional groups were well-tolerated, affording a vast array of chiral cyclopropanes with high enantioselectivities. We also demonstrated that the turnover numbers of the current reaction could be up to 335.
Keywords: Asymmetric Catalysis; Chiral Bidentate Boryl Ligand; Cyclopropane; C−H Borylation; Synthetic Method.
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