The Genus Cryptocarya: A Review on Phytochemistry and Pharmacological Activities

Chem Biodivers. 2023 Mar;20(3):e202201102. doi: 10.1002/cbdv.202201102. Epub 2023 Feb 23.

Abstract

Cryptocarya (the laurel family) is a large genus of great economic plants found in tropics and subtropics. Plants of this genus are a rich resource of essential oils, and pharmacological compounds. An overview of phytochemistry and pharmacological aspect is not yet available. This review aims to establish insightful information on phytochemistry, and pharmacological values. The literature collection is based on keywords 'Cryptocarya', 'phytochemistry', and 'pharmacology' using a broad panel of scientific sources, such as Google Scholar, Sciencedirect, and Wiley. Since the 1950s, Cryptocarya plants have been the main object in various phytochemical studies, by which about 390 metabolite compounds were isolated. Alkaloids, α-pyrones, and flavonoids could be seen as the main classes of Cryptocarya isolates. Cryptocarya constituents displayed potential pharmacological values such as anti-inflammatory, antimicrobial, antioxidative, antiviral, vasorelaxant activities, especially cytotoxicity.

Keywords: Cryptocarya; Lauraceae; cytotoxicity; pharmacology; phytochemistry.

Publication types

  • Review

MeSH terms

  • Cryptocarya*
  • Ethnopharmacology
  • Oils, Volatile* / pharmacology
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacology
  • Phytotherapy / methods
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology

Substances

  • Plant Extracts
  • Phytochemicals
  • Oils, Volatile