Gaps in Depression Symptom Management for Patients With Head and Neck Cancer

Laryngoscope. 2023 Oct;133(10):2638-2646. doi: 10.1002/lary.30595. Epub 2023 Feb 7.

Abstract

Objective: To understand practice patterns and identify care gaps within a large-scale depression screening program for patients with head and neck cancer (HNC).

Study design: Retrospective cohort study.

Methods: This was a population-based study of adults diagnosed with a HNC between January 2007 and October 2020. Each patient was observed from time of first symptom assessment until end of study date, or death. The exposure of interest was a positive depressive symptom screen on the Edmonton Symptom Assessment System (ESAS). Outcomes of interest included psychiatry/psychology assessment, social work referral, or palliative care assessment. Cause specific hazard models with a time-varying exposure were used to investigate the exposure-outcome relationships.

Results: Of 14,054 patients with HNC, 9016 (64.2%) reported depressive symptoms on at least one ESAS assessment. Within 60 days of first reporting depressive symptoms, 223 (2.7%) received a psychiatry assessment, 646 (7.9%) a social work referral, and 1131 (13.9%) a palliative care assessment. Rates of psychiatry/psychology assessment (HR 3.15 [95% CI 2.67-3.72]), social work referral (HR 1.83 [95% CI 1.64-2.02]), and palliative care assessment (HR 2.34 [95% CI 2.19-2.50]) were higher for those screening positive for depression. Certain patient populations were less likely to receive an assessment including the elderly, rural residents, and those without a prior psychiatric history.

Conclusion: A high proportion of head and neck patients report depressive symptoms, though this triggers a referral in a small number of cases. These data highlight areas for improvement in depression screening care pathways.

Level of evidence: 3 Laryngoscope, 133:2638-2646, 2023.

Keywords: cancer; depression; mental health; patient-reported outcomes; psychiatric utilization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Depression / diagnosis
  • Depression / etiology
  • Depression / psychology
  • Head and Neck Neoplasms* / complications
  • Head and Neck Neoplasms* / diagnosis
  • Head and Neck Neoplasms* / therapy
  • Humans
  • Neoplasms*
  • Palliative Care
  • Psychiatric Status Rating Scales
  • Retrospective Studies
  • Symptom Assessment

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