Increased RSV-A Bronchiolitis Severity in RSV-Infected Children Admitted to a Reference Center in Catalonia (Spain) Between 2014 and 2018

Jorgina Vila; Esther Lera; Paula Peremiquel-Trillas; Cristina Andrés; Laia Martínez; Irene Barceló; Ariadna Carsi; Joan Balcells; José Ángel Rodrigo-Pendás; Pere Soler-Palacín; Carlos Rodrigo; Andrés Antón

doi:10.1093/jpids/piad009

Increased RSV-A Bronchiolitis Severity in RSV-Infected Children Admitted to a Reference Center in Catalonia (Spain) Between 2014 and 2018

J Pediatric Infect Dis Soc. 2023 Apr 18;12(3):180-183. doi: 10.1093/jpids/piad009.

Authors

Jorgina Vila^{1

2

3}, Esther Lera^{2

4}, Paula Peremiquel-Trillas^{5

6}, Cristina Andrés⁷, Laia Martínez⁸, Irene Barceló⁸, Ariadna Carsi¹, Joan Balcells^{2

9}, José Ángel Rodrigo-Pendás⁵, Pere Soler-Palacín^{2

3

10}, Carlos Rodrigo^{2

11

12}, Andrés Antón⁶

Affiliations

¹ Pediatric Hospital Medicine, Department of Pediatrics, Hospital Infantil Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
² Department of Pediatrics, Obstetrics and Gynecology, Preventive Medicine and Public Health, Faculty of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
³ Infection in Immunocompromised Pediatric Patients, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
⁴ Pediatric Emergency Unit, Department of Pediatrics, Hospital Infantil Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
⁵ Preventive Medicine and Epidemiology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
⁶ Research Unit Infections and Cancer, Institut Català d'Oncologia, Avinguda de la Gran Via de l'Hospitalet, Barcelona, Spain.
⁷ Respiratory Viruses Unit, Virology Section, Microbiology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
⁸ Department of Pediatrics, Hospital Infantil Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
⁹ Pediatric Critical Care Unit, Department of Pediatrics, Hospital Infantil Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
¹⁰ Pediatric Infectious Diseases and Immunodeficiencies Unit, Department of Pediatrics, Hospital Infantil Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
¹¹ Department of Pediatrics, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain.
¹² Germans Trias i Pujol Research Institute, Carretera de Can Ruti, Camí de les Escoles, Barcelona, Spain.

PMID: 36744919
DOI: 10.1093/jpids/piad009

Abstract

Between 2014 and 2018, we evaluated the severity of 687 cases of bronchiolitis caused by respiratory syncytial virus (RSV) in Catalonia, Spain. Compared to RSV-B, RSV-A cases required intensive care (adjusted relative risk (aRR) = 1.44, p < 0.01) and respiratory support (aRR = 1.07, p < 0.01) more often; hospital stay was one day longer (p < 0.01). Subgroup identification may aid clinical evaluation and seasonal healthcare planning.

Keywords: RSV-A; bronchiolitis; bronchiolitis severity; respiratory infections; respiratory syncytial virus.

© The Author(s) 2023. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

MeSH terms

Bronchiolitis, Viral* / diagnosis
Bronchiolitis, Viral* / epidemiology
Female
Hospitalization
Humans
Male
Respiratory Syncytial Virus Infections* / diagnosis
Respiratory Syncytial Virus Infections* / epidemiology
Respiratory Syncytial Virus, Human*
Retrospective Studies
Spain / epidemiology

Abstract

MeSH terms

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