Low-Level Laser Therapy in the Treatment of Autoimmune Thyroiditis

Nikoo Hossein-Khannazer; Mandana Kazem Arki; Liasghar Keramatinia; Mostafa Rezaei-Tavirani

doi:10.34172/jlms.2022.34

Low-Level Laser Therapy in the Treatment of Autoimmune Thyroiditis

J Lasers Med Sci. 2022 Aug 24:13:e34. doi: 10.34172/jlms.2022.34. eCollection 2022.

Authors

Nikoo Hossein-Khannazer^{1

2}, Mandana Kazem Arki², Liasghar Keramatinia^{3

4}, Mostafa Rezaei-Tavirani⁵

Affiliations

¹ Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
² Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
³ Department of Social Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁴ Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁵ Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

Introduction: Autoimmune thyroiditis (AIT) is an autoimmune disorder that is characterized by thyroid gland dysfunction. Low-level laser therapy (LLLT), as a safe and non-invasive intervention, has gained much attention in many clinical applications including pain relief, regenerative medicine, and autoimmune. Methods: In this review, we discuss the effect of LLLT on cellular responses and its application in the treatment of AIT. Such keywords as "low-level laser therapy", "photobiomodulation" and "autoimmune thyroiditis" were used to find studies related to laser therapy in AIT in Google Scholar, PubMed and Medline databases. Results: LLLT reduced thyroid gland inflammation and inhibited immune cell trafficking. LLLT modulated inflammatory responses and improved thyroid gland regeneration. Conclusion: Investigations indicated that besides current treatment strategies, LLLT could be a promising therapeutic approach for the treatment of AIT.

Keywords: Autoimmune disease; Autoimmune thyroiditis; Inflammation; Laser therapy; Low-level laser therapy (LLLT); Photobiomodulation.

Publication types

Review