Surgeon-Performed Point-of-Care Ultrasound in the Diagnosis of Acute Sigmoid Diverticulitis: A Pragmatic Prospective Multicenter Cohort Study

Bogdan D Dumbrava; Hajar S Abdulla; Jorge Pereira; Alan Biloslavo; Mauro Zago; Jamal H Hashem; Nitya Kumar; Martin Corbally; Gary A Bass; Thomas N Walsh

doi:10.7759/cureus.33292

Surgeon-Performed Point-of-Care Ultrasound in the Diagnosis of Acute Sigmoid Diverticulitis: A Pragmatic Prospective Multicenter Cohort Study

Cureus. 2023 Jan 3;15(1):e33292. doi: 10.7759/cureus.33292. eCollection 2023 Jan.

Authors

Affiliations

¹ Department of Surgery, Connolly Hospital, Dublin, IRL.
² Department of Surgery, Royal College of Surgeons in Ireland - Medical University of Bahrain, Busaiteen, BHR.
³ Department of Surgery, Tondela-Viseu Hospital Center, Viseu, PRT.
⁴ Department of Surgery, Cattinara University Hospital, Trieste, ITA.
⁵ Department of Surgery, Policlinico San Pietro, Ponte San Pietro, ITA.
⁶ Department of Epidemiology and Public Health, Royal College of Surgeons in Ireland - Medical University of Bahrain, Busaiteen, BHR.
⁷ Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, Philadelphia, USA.

Abstract

Background and purpose Early diagnosis and risk stratification of sigmoid diverticulitis rely heavily on timely imaging. Computerized tomography (CT), the gold standard diagnostic test, may be delayed due to resource constraints or patient comorbidity. Point-of-care ultrasound (POCUS) has an established role in trauma evaluation, and could potentially diagnose and stage acute diverticulitis, thus shortening the time to definitive treatment. Aims This study aimed to benchmark the accuracy of surgeon-performed POCUS against CT in diagnosing and staging acute diverticulitis. A secondary aim was to evaluate the duration between the POCUS and the confirmatory CT scan report. Patients and methods A pragmatic prospective multicenter cohort study (ClinicalTrials.gov Identifier: NCT02682368) was conducted. Surgeons performed point-of-care ultrasound as first-line imaging for suspected acute diverticulitis. POCUS diagnosis and radiologic Hinchey classification were compared to CT as the reference standard. Results Of 45 patients with suspected acute diverticulitis, POCUS classified 37 (82.2%) as uncomplicated diverticulitis, four (8.8%) as complicated diverticulitis, and four (8.8%) as other diagnoses. The POCUS-estimated modified radiologic Hinchey classification was largely concordant with CT staging with an accuracy of 88.8% (95% CI, 75.95-96.2%), a sensitivity of 100% (95% CI, 90.2- 100%) and a specificity of 44.4% (95% CI, 13.7-78.8%). The positive predictive value (PPV) was 87.8% and the negative predictive value (NPV) was 100%. There was moderate agreement between CT and POCUS, with a Cohen's kappa coefficient of 0.56. The mean delay between CT and POCUS was 9.14 hours (range 0.33 to 43.5). Conclusion We examined the role of POCUS in the management of acute diverticulitis and our findings suggest that it is a promising imaging modality with the potential to reduce radiation exposure and treatment delays. Adding a POCUS training module to the surgical curriculum could enhance diagnosis and expedite the management of acute diverticulitis.

Keywords: abdominal sonography; acute abdomen; diverticulitis; pocus; ultrasound.

Associated data

ClinicalTrials.gov/NCT02682368