Fit for purpose of on-the-road driving and simulated driving: A randomised crossover study using the effect of sleep deprivation

PLoS One. 2023 Feb 2;18(2):e0278300. doi: 10.1371/journal.pone.0278300. eCollection 2023.

Abstract

Introduction: Drivers should be aware of possible impairing effects of alcohol, medicinal substance, or fatigue on driving performance. Such effects are assessed in clinical trials, including a driving task or related psychomotor tasks. However, a choice between predicting tasks must be made. Here, we compare driving performance with on-the-road driving, simulator driving, and psychomotor tasks using the effect of sleep deprivation.

Method: This two-way cross over study included 24 healthy men with a minimum driving experience of 3000km per year. Psychomotor tasks, simulated driving, and on-the-road driving were assessed in the morning and the afternoon after a well-rested night and in the morning after a sleep-deprived night. Driving behaviour was examined by calculating the Standard Deviation of Lateral Position (SDLP).

Results: SDLP increased after sleep deprivation for simulated (10cm, 95%CI:6.7-13.3) and on-the-road driving (2.8cm, 95%CI:1.9-3.7). The psychomotor test battery detected effects of sleep deprivation in almost all tasks. Correlation between on-the-road tests and simulator SDLP after a well-rested night (0.63, p < .001) was not present after a night of sleep deprivation (0.31, p = .18). Regarding the effect of sleep deprivation on the psychomotor test battery, only adaptive tracking correlated with the SDLP of the driving simulator (-0.50, p = .02). Other significant correlations were related to subjective VAS scores.

Discussion: The lack of apparent correlations and difference in sensitivity of performance of the psychomotor tasks, simulated driving and, on-the-road driving indicates that the tasks may not be interchangeable and may assess different aspects of driving behaviour.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Automobile Driving*
  • Awareness
  • Cross-Over Studies
  • Ethanol / pharmacology
  • Fatigue
  • Humans
  • Male
  • Psychomotor Performance
  • Sleep Deprivation*

Substances

  • Ethanol

Grants and funding

The author(s) received no specific funding for this work.